Leisure-time aerobic physical activity and the risk of diabetes-related mortality: An analysis of effect modification by race-ethnicity
Aims: To examine the relationship between aerobic moderate-to-vigorous intensity leisure-time physical activity (LTPA) and the risk of diabetes-related mortality in the NHANES III (1988–1994) while considering potential effect modification by race-ethnicity. Methods: The study sample (n = 14,006) included adults, 20–79 years of age, with Mobile Examination Center (MEC) data. An age-standardized physical activity score (PAS) was calculated from the self-reported frequency and intensity of 12 leisure-time aerobic activities. Three categories of PA were examined: inactive (PAS = 0), insufficiently active (PAS >0–<10), and active (PAS ≥10). Diabetes-related mortality was defined as death from diabetes mellitus. Cox Proportional Hazard models were used all analyses. Results: A statistically significant reduction in risk was found for insufficiently active (HR 0.59, 95% CI 0.40–0.90) and active non-Hispanic black (NHB) (HR 0.54, 95% CI 0.34–0.88). Among active non-Hispanic white (NHW), a similar pattern of risk reduction was found, however, this relationship was borderline significance (HR 0.59, 95% CI 0.35–1.02, p = 0.06). Conclusions: Any volume of aerobic LTPA is beneficial in terms of reducing the risk of diabetes-related mortality. However, these benefits may differ by racial-ethnic group, with further research on health disparities in the area of PA being warranted.
Journal of Diabetes and its Complications
Digital Object Identifier (DOI)
Boyer, W. R., Ehrlich, S.F., Crouter, S.E., Churilla, J.R., Fitzhugh, E. C. (2021) Leisure-time aerobic physical activity and the risk of diabetes-related mortality: An analysis of effect modification by race-ethnicity. Journal of Diabetes and its Complications, 35(1), 107763. 10.1016/j.jdiacomp.2020.107763