Title

Leisure-time aerobic physical activity and the risk of diabetes-related mortality: An analysis of effect modification by race-ethnicity

Document Type

Article

Publication Date

1-1-2021

Subject Area

ARRAY(0x564abf7408d0)

Abstract

Aims: To examine the relationship between aerobic moderate-to-vigorous intensity leisure-time physical activity (LTPA) and the risk of diabetes-related mortality in the NHANES III (1988–1994) while considering potential effect modification by race-ethnicity. Methods: The study sample (n = 14,006) included adults, 20–79 years of age, with Mobile Examination Center (MEC) data. An age-standardized physical activity score (PAS) was calculated from the self-reported frequency and intensity of 12 leisure-time aerobic activities. Three categories of PA were examined: inactive (PAS = 0), insufficiently active (PAS >0–<10), and active (PAS ≥10). Diabetes-related mortality was defined as death from diabetes mellitus. Cox Proportional Hazard models were used all analyses. Results: A statistically significant reduction in risk was found for insufficiently active (HR 0.59, 95% CI 0.40–0.90) and active non-Hispanic black (NHB) (HR 0.54, 95% CI 0.34–0.88). Among active non-Hispanic white (NHW), a similar pattern of risk reduction was found, however, this relationship was borderline significance (HR 0.59, 95% CI 0.35–1.02, p = 0.06). Conclusions: Any volume of aerobic LTPA is beneficial in terms of reducing the risk of diabetes-related mortality. However, these benefits may differ by racial-ethnic group, with further research on health disparities in the area of PA being warranted.

Publication Title

Journal of Diabetes and its Complications

Volume

35

Issue

1

Digital Object Identifier (DOI)

10.1016/j.jdiacomp.2020.107763

ISSN

10568727

E-ISSN

1873460X

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