A 100-channel hermetically sealed implantable device for chronic wireless neurosensing applications
A 100-channel fully implantable wireless broadband neural recording system was developed. It features 100 parallel broadband (0.1 Hz-7.8 kHz) neural recording channels, a medical grade 200 mAh Li-ion battery recharged inductively at 150 kHz , and data telemetry using 3.2 GHz to 3.8 GHz FSK modulated wireless link for 48 Mbps Manchester encoded data. All active electronics are hermetically sealed in a titanium enclosure with a sapphire window for electromagnetic transparency. A custom, high-density configuration of 100 individual hermetic feedthrough pins enable connection to an intracortical neural recording microelectrode array. A 100 MHz bandwidth custom receiver was built to remotely receive the FSK signal and achieved-77.7 dBm sensitivity with 10-8 BER at 48 Mbps data rate. ESD testing on all the electronic inputs and outputs has proven that the implantable device satisfies the HBM Class-1B ESD Standard. In addition, the evaluation of the worst-case charge density delivered to the tissue from each I/O pin verifies the patient safety of the device in the event of failure. Finally, the functionality and reliability of the complete device has been tested on-bench and further validated chronically in ongoing freely moving swine and monkey animal trials for more than one year to date. © 2007-2012 IEEE.
IEEE Transactions on Biomedical Circuits and Systems
Digital Object Identifier (DOI)
Yin, Borton, D. A., Aceros, J., Patterson, W. R., & Nurmikko, A. V. (2013). A 100-Channel Hermetically Sealed Implantable Device for Chronic Wireless Neurosensing Applications. IEEE Transactions on Biomedical Circuits and Systems, 7(2), 115–128. https://doi.org/10.1109/TBCAS.2013.2255874