Prevalence of STOP BANG questionnaire and association with major cardiovascular events in hospitalized population: is it enough with currently used cardiovascular risk measurements?

Authors

Gonzalo Labarca, Universidad San Sebastián
Gabriel Valdivia, Universidad de Concepcion
Aileen Oñate, Universidad San Sebastián
Camila Navarrete, Universidad San Sebastián
Jose Araya, Universidad San Sebastián
Isabel Fernandez-Bussy, University of North Florida
Jorge Dreyse, Clinica Las Condes
Jorge Jorquera, Clinica Las Condes

Document Type

Article

Publication Date

9-1-2019

Abstract

Cardiovascular risk (CR) is associated with obstructive sleep apnea hypopnea syndrome (OSAHS). This association enhances the risk of major adverse cardiovascular events (MACE); nevertheless, data from hospitalized populations and interactions among these conditions remain unclear. Purpose: To evaluate the risk of MACE in the population with risk of OSAHS using the STOP-BANG questionnaire. Methods: We performed a prospective study in an academic hospital from 2017 to 2018. Data included demography, admissions, STOP-BANG score and CR using AHA scores. The primary outcome was risk of MACE in participants with low risk of OSAHS (STOP-BANG 0–2 points), risk of OSAHS (≥3 points) and risk of moderate/severe OSAHS (≥5 points). Risk of MACE was evaluated using odds ratios (OR), and average CR was evaluated using the t-test. Results: A total of 441 participants were included. The cumulative prevalence of STOP BANG ≥3 points was 80.9%, and that of ≥5 points was 41.6%. OR of MACE ≥3 points was 3.93 (CI 2.08–7.24) (p < 0.001) compared with <3 points, and Average CR was 10.91% (SD ± 2.13) at <3 points versus 24.3% (SD ± 1.24) for ≥3 points for ≥5 points OR of MACE was 1.72 (CI 1.18–2.59) (p = 0.005) and average CR was 26.14% (SD ± 1.63). However, after multivariable analysis, gender differences and previous heart failure were independently associated to MACE. Conclusion: The risk of OSAHS in the hospitalized population is high. This population has a higher risk of MACE and higher CRs than do low-risk participants. Conversely, gender and heart failure are potential cofounders.

Publication Title

Sleep Medicine

Volume

61

First Page

82

Last Page

87

Digital Object Identifier (DOI)

10.1016/j.sleep.2019.02.019

PubMed ID

31416696

ISSN

13899457

E-ISSN

18785506

Citation Information

Labarca, G., Valdivia, G., Onate, A., Navarrete, C., Araya, J., Fernandez-Bussy, I., Dreyse, J., Jorquera, J. (2019) Prevalence of STOP BANG questionnaire and association with major cardiovascular events in hospitalized population: is it enough with currently used cardiovascular risk measurements? Sleep Medicine, 61, 82-87