Facile Access to Diverse Libraries of Internal Alkynes via Sequential Iododediazoniation/Decarboxylative Sonogashira Reaction in Imidazolium ILs without Ligand or Additive
Document Type
Article
Publication Date
3-14-2019
Abstract
Convenient access to diverse libraries of internal alkynes via decarboxylative Sonogashira reaction of alkynyl-carboxylic acids with iodoarenes, employing imidazolium-ILs as solvent, along with piperidine-appended imidazolium [PAIM][NTf 2 ] as task-specific basic IL is demonstrated, without the need for any ligand or additive. The feasibility to perform these reactions by sequential one-pot iododediazoniation/decarboxylative Sonogashira reaction is also shown, and the scope of the methods is underscored by providing 29 examples. The potential for recycling and reuse of the IL solvent is also examined.
Publication Title
European Journal of Organic Chemistry
Volume
2019
Issue
10
First Page
2061
Last Page
2064
Digital Object Identifier (DOI)
10.1002/ejoc.201900093
ISSN
1434193X
E-ISSN
10990690
Citation Information
Prabhala, P., Savanur, H.M., Kalkhambkar, R.G., Laali, K.K. (2019) Facile Access to Diverse Libraries of Internal Alkynes via Sequential Iododediazoniation/Decarboxylative Sonogashira Reaction in Imidazolium ILs without Ligand or Additive. European Journal of Organic Chemistry, 2019(10), 2061-2064.