Cardiopulmonary exercise testing in patients with pulmonary hypertension: Clinical recommendations based on a review of the evidence
Document Type
Article
Publication Date
3-3-2016
Abstract
Pulmonary hypertension (PH) remains an ominous diagnosis despite advances in pharmacological and surgical therapy. Early and effective diagnosis is important for clinicians making treatment determinations and patients wishing to understand the prognostic implications of their illness. Cardiopulmonary exercise testing (CPX) has the power to reveal the underlying pathophysiological consequences of the disease process. Research, especially over the last 10-15 years, has demonstrated the utility of this tool. Several CPX variables have been shown to be consistently altered in patients with PH and more so as severity of disease increases. However, to further enhance clinical application, additional research is needed to better define optimal CPX measures and associated cutoff values. This paper gives class-based recommendations with associated levels of evidence for the use of CPX in the PH patient population.
Publication Title
Expert Review of Respiratory Medicine
Volume
10
Issue
3
First Page
279
Last Page
295
Digital Object Identifier (DOI)
10.1586/17476348.2016.1144475
PubMed ID
26789612
ISSN
17476348
E-ISSN
17476356
Citation Information
Pinkstaff, Burger, C. D., Daugherty, J., Bond, S., & Arena, R. (2016). Cardiopulmonary exercise testing in patients with pulmonary hypertension: clinical recommendations based on a review of the evidence. Expert Review of Respiratory Medicine, 10(3), 279–295. https://doi.org/10.1586/17476348.2016.1144475