Gender differences in C-reactive protein and muscle strengthening activity

Document Type

Article

Publication Date

12-1-2015

Abstract

Background: Few studies have examined the gender differences between C-reactive protein (CRP) and muscle strengthening activity (MSA). Methods: The sample (n = 7533) included U.S. adult (≥20 years of age).participants in the 1999-2004 National Health and Nutrition Examination Survey (NHANES). Created categories of MSA participation included no MSA (referent group), some MSA (≥1 to /week), and meeting the 2008 Department of Health and Human Services (DHHS) recommendation (≥2 days/week). The dependent variable was elevated CRP (>3 to 10 mg/L). Results: Analysis revealed significantly lower odds of having elevated CRP for women reporting some MSA (OR 0.64; 95% CI 0.44-0.93, P =.0191). Significantly lower odds of men having elevated CRP was observed in those reporting MSA volumes meeting the DHHS recommendation (OR 0.72; 95% CI 0.59-0.88, P =.0019). Following adjustment for waist circumference (WC) these odds remained significant in men but not women. Conclusions: These results suggest that WC may mediate the associations between MSA and CRP and this relationship may be stronger in women.

Publication Title

Journal of Physical Activity and Health

Volume

12

Issue

12

First Page

1582

Last Page

1588

Digital Object Identifier (DOI)

10.1123/jpah.2014-0491

PubMed ID

26963135

ISSN

15433080

E-ISSN

15435476

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