Gender differences in C-reactive protein and muscle strengthening activity
Background: Few studies have examined the gender differences between C-reactive protein (CRP) and muscle strengthening activity (MSA). Methods: The sample (n = 7533) included U.S. adult (≥20 years of age).participants in the 1999-2004 National Health and Nutrition Examination Survey (NHANES). Created categories of MSA participation included no MSA (referent group), some MSA (≥1 to /week), and meeting the 2008 Department of Health and Human Services (DHHS) recommendation (≥2 days/week). The dependent variable was elevated CRP (>3 to 10 mg/L). Results: Analysis revealed significantly lower odds of having elevated CRP for women reporting some MSA (OR 0.64; 95% CI 0.44-0.93, P =.0191). Significantly lower odds of men having elevated CRP was observed in those reporting MSA volumes meeting the DHHS recommendation (OR 0.72; 95% CI 0.59-0.88, P =.0019). Following adjustment for waist circumference (WC) these odds remained significant in men but not women. Conclusions: These results suggest that WC may mediate the associations between MSA and CRP and this relationship may be stronger in women.
Journal of Physical Activity and Health
Digital Object Identifier (DOI)
Richardson, Johnson, T. M., Katzmarzyk, P. T., Ford, E. S., Boyer, W. R., & Churilla, J. R. (2015). Gender Differences in C-Reactive Protein and Muscle Strengthening Activity. Journal of Physical Activity & Health, 12(12), 1582–1588. https://doi.org/10.1123/jpah.2014-0491