A Flexible Strategy for Modular Synthesis of Curcuminoid-BF2/Curcuminoid Pairs and Their Comparative Antiproliferative Activity in Human Cancer Cell Lines
Document Type
Article
Publication Date
2-17-2020
Abstract
A facile protocol that enables synthetic interconversion of CUR-BF2 and CUR compounds is described that significantly widens the preparative scope of curcuminoids, providing access to larger libraries of compounds, thus enabling comparative antiproliferative and apoptotic study of a larger library of synthetic analogs in cancer cell lines.
Publication Title
ChemMedChem
Volume
15
Issue
4
First Page
354
Last Page
362
Digital Object Identifier (DOI)
10.1002/cmdc.201900640
PubMed ID
31875350
ISSN
18607179
E-ISSN
18607187
Citation Information
Abonia, R., Laali, K. K., Raja Somu, D., Bunge, S. D., & Wang, E. C. (2020). A Flexible Strategy for Modular Synthesis of Curcuminoid-BF2 /Curcuminoid Pairs and Their Comparative Antiproliferative Activity in Human Cancer Cell Lines. ChemMedChem, 15(4), 354–362. https://doi.org/10.1002/cmdc.201900640
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