Title

A Flexible Strategy for Modular Synthesis of Curcuminoid-BF2/Curcuminoid Pairs and Their Comparative Antiproliferative Activity in Human Cancer Cell Lines

Document Type

Article

Publication Date

2-17-2020

Subject Area

ARRAY(0x55c827006758)

Abstract

A facile protocol that enables synthetic interconversion of CUR-BF2 and CUR compounds is described that significantly widens the preparative scope of curcuminoids, providing access to larger libraries of compounds, thus enabling comparative antiproliferative and apoptotic study of a larger library of synthetic analogs in cancer cell lines.

Publication Title

ChemMedChem

Volume

15

Issue

4

First Page

354

Last Page

362

Digital Object Identifier (DOI)

10.1002/cmdc.201900640

PubMed ID

31875350

ISSN

18607179

E-ISSN

18607187

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